BioFoundation-G™ Multiple Vitamin & Mineral Formula 180 Tablets NPN: 80051438

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  • A full spectrum of vitamins and minerals
  • Provides rate-limiting nutrients for glutathione production, necessary for xenobiotic detoxification
  • Contains clinical doses of resveratrol, lipoic acid, CoQ10, milk thistle, and green tea extract
  • Broad-spectrum antioxidant support, including bilberry and citrus extracts, lipoic acid, lycopene, and lutein
  • Highly bioactive and bioavailable nutrients, such as pyridoxal-5-phosphate and vitamin K2 (Menaquinone 7)

Feature Summary

BioFoundation-G is a comprehensive vitamin and mineral supplement to support healthy living in the modern world. A broad-spectrum and highly bioavailable multivitamin and mineral, BioFoundation-G’s formulation uses clinically driven research to provide the nutritional foundation needed for the modern environment. This complete multivitamin and mineral formula contains clinical doses of nutrients such as N-acetyl-cysteine and R-alpha-lipoic acid, well established to increase cellular levels of glutathione, the most prevalent intercellular antioxidant.1,2,3 Glutathione is one of the most important conjugators of numerous environmental and endogenous toxins. It is known to be depleted not only by xenobiotics but also by chronic conditions such as inflammatory and neurodegenerative diseases.4,5,6,7,8

Glutathione support is linked to lower rates of cell death and apoptosis.9 BioFoundation-G provides physiologically relevant doses of hepatoprotectors such as milk thistle, antioxidants, mitochondrial bioenergetic enhancers such as CoQ10, and co-factors for critical detoxification enzymes.10,11 It also provides the biological modifiers natural trans-resveratrol and green tea phytosome, two nutrients shown to have anti-inflammatory, weight management, anti-aging, cardiovascular, and stress-related benefits.12,13,14,15


Medicinal Ingredients

Each Tablet Contains: Daily Dose:
Vitamin A (Palmitate) 500 IU (150 mcg RAE) 1500 IU (450 mcg RAE)
Vitamin B1 (Thiamine Hydrochloride) 4.2 mg 12.6 mg
Vitamin B2 (Riboflavin) 4.2 mg 12.6 mg
Vitamin B3 (Niacin) 12.5 mg 37.5 mg
Vitamin B3 (Niacinamide) 33.3 mg 100 mg
Vitamin B5 (Pantothenic Acid) (Calcium d-Pantothenate) 16.7 mg 50 mg
Vitamin B6 (Pyridoxine Hydrochloride) (Pyridoxal 5-Phosphate) 2.5 mg 7.5 mg
Biotin 8.3 mcg 25 mcg
Betaine Hydrochloride 16.7 mg 50 mg
Folate (from (6S)-5-Methyltetrahydrofolic Acid (MTHF), Glucosamine Salt, Quatrefolic®) 83 mcg 249 mcg
Vitamin B12 (Methylcobalamin) 167 mcg 501 mcg
Para-Aminobenzoic Acid (PABA) 4.2 mg 12.6 mg
Choline (Bitartrate) 4.2 mg 12.6 mg
Inositol 4.2 mg 12.6 mg
Vitamin C (Ascorbic Acid) 167 mg 501 mg
Vitamin D3 (Cholecalciferol) 333 IU (8.3 mcg) 999 IU (25 mcg)
Vitamin E (d-Gamma Tocopherol) 33.3 mg 100 mg
Vitamin K2 (Menaquinone) (MK-7) (Natto Bean) 7.5 mcg 22.5 mcg
Boron (Citrate) 41.7 mcg 125 mcg
Calcium (HVP* Chelate) 16.7 mg 50 mg
Chromium (Polynicotinate) 33.3 mcg 100 mcg
Copper (HVP* Chelate) 170 mcg 510 mcg
Iodine (Ascophyllum nodosum) (whole plant) 50 mcg 150 mcg
Magnesium (HVP* Chelate) 33.3 mg 100 mg
Manganese (Citrate) 0.8 mg 2.4 mg
Molybdenum (Citrate) 66.7 mcg 200 mcg
Potassium (Citrate) 6.8 mg 20.4 mg
Selenium (Selenomethionine) 33.3 mcg 100 mcg
Vanadium (Citrate) 2.5 mcg 7.5 mcg
Zinc (Citrate) 2.5 mg 7.5 mg
Bilberry Extract (Vaccinium myrtillus) (36% Anthocyanosides) (fruit) 6.6 mg 20 mg
Citrus Bioflavonoids 4:1 Extract (Citrus limon, Citrus sinensis, Citrus paradisi, Citrus reticulata, Citrus aurantiifolia) (fruit) 8.3 mg 25 mg
Coenzyme Q10 (Microorganism) (whole cell) 8.3 mg 25 mg
Green Tea Phytosome® (Camellia sinensis, Glycine max) (13% EGCG**) (leaf, seed) 8.3 mg 25 mg
Hesperidin (Citrus sinensis) (fruit) 4.2 mg 12.6 mg
Lutein (Tagetes erecta) (flower) 550 mcg 1650 mcg
Lycopene (Lycopersicon esculentum) (fruit) 280 mcg 840 mcg
Silybin Phytosome® (Silybum marianum, Glycine max) (15% Silybin) (fruit, seed) 25 mg 75 mg
N-Acetyl-L-Cysteine 25 mg 75 mg
R-Alpha-Lipoic Acid 41.7 mg 125 mg
ResveratrolRich® Proprietary Blend [Wine Grape (Vitis vinifera) (fruit), Purified Japanese Knotweed (Polygonum cuspidatum) (root)] 33.3 mg 100 mg
Providing Natural Trans-Resveratrol 16.7 mg 50 mg
*HVP: Hydrolyzed Vegetable Protein **EGCG: epigallocatechin-3-gallate

Non-Medicinal Ingredients

Microcrystalline cellulose, croscarmellose sodium, coating (carbohydrate gum [cellulose], glycerin), vegetable grade magnesium stearate (lubricant).


Contains no artificial colors, preservatives, or sweeteners; no dairy, sugar, wheat, gluten, yeast, egg, fish, shellfish, salt, tree nuts, or GMOs. Sealed for your protection. Do not use if seal is broken. For freshness, store in a cool, dry place.

Recommended Use:

3 tablets per day with meals, 2 hours before or after taking other medications, or as directed by a health care practitioner.


Consult a health care practitioner if you are taking blood thinners, or if you are pregnant or breastfeeding. Consult a health care practitioner prior to use if you have diabetes or kidney stones, or if you are taking sulfonamides or blood pressure medication. Consult a health care practitioner prior to use if you are taking prescription medication, as resveratrol may alter the effectiveness of these medications. Hypersensitivity (e.g., allergy) has been known to occur, in which case discontinue use. Do not use this product if you are taking antibiotics or nitroglycerin. Keep out of reach of children.

Drug Interactions

Vitamin K supplementation may decrease the efficacy of warfarin or require more close monitoring of its administration.16 This product contains nutrients known to reduce hypertension and hyperglycemia and may require lower dosing or discontinuation of related medications.14,16

  1. Atkuri, K. R., Mantovani, J. J., Herzenberg, L. A., et al. (2007). N-Acetylcysteine–a safe antidote for cysteine/glutathione deficiency. Current opinion in pharmacology7(4), 355–359.
  2. Shay, K. P., Moreau, R. F., Smith, E. J., et al. (2009). Alpha-lipoic acid as a dietary supplement: molecular mechanisms and therapeutic potential. Biochimica et biophysica acta1790(10), 1149–1160.
  3. Becker, K., Pons-Kühnemann, J., Fechner, A., et al. (2005). Effects of antioxidants on glutathione levels and clinical recovery from the malnutrition syndrome kwashiorkor – a pilot study. Redox Report10(4), 215–226.
  4. Awasthi, Y. C., Chaudhary, P., Vatsyayan, R., et al. (2009). Physiological and pharmacological significance of glutathione-conjugate transport. Journal of toxicology and environmental health. Part B, Critical reviews12(7), 540–551.
  5. Ludewig, G., Srinivasan, A., &Robertson, L. W. (2000). Mechanisms of toxicity of PCB metabolites: generation of reactive oxygen species and glutathione depletion. Central European journal of public health8 Suppl, 15–17.
  6. Ahmed, T., Tripathi, A. K., Ahmed, R. S., et al. (2008). Endosulfan-induced apoptosis and glutathione depletion in human peripheral blood mononuclear cells: Attenuation by N-acetylcysteine. Journal of biochemical and molecular toxicology22(5), 299–304.
  7. Lee, D. H., &Jacobs, D. R., Jr (2009). Serum gamma-glutamyltransferase: new insights about an old enzyme. Journal of epidemiology and community health63(11), 884–886.
  8. Ljubisavljevic, S., Stojanovic, I., Cvetkovic, T., et al. (2014). Glutathione homeostasis disruption of erythrocytes, but not glutathione peroxidase activity change, is closely accompanied with neurological and radiological scoring of acute CNS inflammation. Neuroimmunomodulation21(1), 13–20.
  9. Circu, M. L., &Aw, T. Y. (2012). Glutathione and modulation of cell apoptosis. Biochimica et biophysica acta1823(10), 1767–1777.
  10. Rosenfeldt, F., Marasco, S., Lyon, W., et al. (2005). Coenzyme Q10 therapy before cardiac surgery improves mitochondrial function and in vitro contractility of myocardial tissue. The Journal of thoracic and cardiovascular surgery129(1), 25–32.
  11. Kiruthiga, P. V., Shafreen, R. B., Pandian, S. K., et al. (2007). Silymarin protection against major reactive oxygen species released by environmental toxins: exogenous H2O2 exposure in erythrocytes. Basic &clinical pharmacology &toxicology100(6), 414–419.
  12. Wightman, E. L., Haskell-Ramsay, C., Reay, J. L., et al. (2015). The effects of chronic trans-resveratrol supplementation on aspects of cognitive function, mood, sleep, health and cerebral blood flow in healthy, young humans. The British Journal of Nutrition, 114(9), 1427­–1437.
  13. Hoseini, A., Namazi, G., Farrokhian, A., et al. (2019). The effects of resveratrol on metabolic status in patients with type 2 diabetes mellitus and coronary heart disease. Food &function10(9), 6042–6051.
  14. Brasnyó, P., Molnár, G. A., Mohás, M., et al. (2011). Resveratrol improves insulin sensitivity, reduces oxidative stress and activates the Akt pathway in type 2 diabetic patients. The British journal of nutrition106(3), 383–389
  15. Gilardini, L., Pasqualinotto, L., Di Pierro, F., et al. (2016). Effects of Greenselect Phytosome® on weight maintenance after weight loss in obese women: a randomized placebo-controlled study. BMC complementary and alternative medicine16, 233.
  16. Ford, S. K., Misita, C. P., Shilliday, B. B., et al. (2007). Prospective study of supplemental vitamin K therapy in patients on oral anticoagulants with unstable international normalized ratios. Journal of thrombosis and thrombolysis24(1), 23–27.