Description
Benefits
- Comprehensive blend of antioxidants and nutrients to support mitochondrial function in sperm, shown to optimize sperm maturation, count, and motility
- Provides the most bioavailable forms of nutrients, including pyridoxal 5’-phosphate, vitamin D3, methylcobalamin, and L-5-methyltetrahydrofolate
- Provides clinically relevant doses of nutrients for male fertility
- Supports glutathione production, essential for detoxification of many toxins frequently associated with impaired fertility
- Decreases oxidative stress, which is closely linked to male infertility
Feature Summary
Mito Motile is a comprehensive male reproductive fertility support kit. The kit contains clinically relevant doses of vitamins and minerals, antioxidants and amino acids, essential fatty acids, and critical supportive nutrients for healthy male function. Mitochondrial dysfunction has been linked to increased oxidative damage, which in turn is closely linked with male infertility.1,2 Mito Motile has multiple mitochondrial optimizers, including L-carnitine, PQQ-10®, and CoQ10, shown to increase pregnancy rates and various parameters of sperm function.3-5 It provides potent antioxidants, such as resveratrol, vitamin E, selenium, and N-acetylcysteine, nutrients shown to protect against toxins that target spermatogenesis and improve sperm counts alone and when combined with clomiphene citrate.6,7 It also provides N-acetyl-L-cysteine (a building block for the production of glutathione – a potent antioxidant) to decrease oxidative stress and improve sperm quality.8,9 It contains the mineral zinc, critical for sperm count and motility,10,11 and for preventing oxidative stress and sperm DNA fragmentation.11 Its comprehensive nutritional support also includes clinically relevant doses of the omega-3 fatty acids DHA and EPA, shown in human trials to improve sperm cell total count and concentration in men with idiopathic oligoasthenoteratospermia, as well as B vitamins for supporting energy production.12-14
Medicinal Ingredients
| Each Packet Contains One of Each of the Following Supplements: L-Carnitine; Resveratrol with Grape Seed Extract; Vitamin E 400 with Selenium; Zinc Citrate; PQQ-10®; OptiMega-3® with Vitamin D3; N-Acetyl-L-Cysteine; B Complex-Pro. | |
| L-Carnitine | |
| Each Capsule Contains: | |
| L-Carnitine (Tartrate) | 500 mg |
| Non-medicinal Ingredients: Vegetarian capsule (carbohydrate gum [cellulose], purified water), silica, microcrystalline cellulose, vegetable grade magnesium stearate (lubricant). | |
| Resveratrol with Grape Seed Extract | |
| Each Capsule Contains: | |
| Japanese Knotweed Extract (Fallopia japonica) (root) (20% Trans-Resveratrol) | 200 mg |
| Grape Seed Extract (Vitis vinifera) (seed) (80% Oligomeric Proanthocyanidins) | 25 mg |
| Non-medicinal Ingredients: Gelatin capsule (gelatin, purified water), microcrystalline cellulose, vegetable grade magnesium stearate (lubricant), silica. | |
| Vitamin E 400 with Selenium | |
| Each Tablet Contains: | |
| Vitamin E (d-Alpha Tocopheryl Acid Succinate) | 400 IU (268 mg AT*) |
| Selenium (Yeast) | 100 mcg |
| Vitamin C (Ascorbic Acid) | 100 mg |
| Manganese (Gluconate) | 10 mg |
| *Alpha Tocopherol | |
| Non-medicinal Ingredients: Dibasic calcium phosphate dihydrate, microcrystalline cellulose, silica, croscarmellose sodium, vegetable grade magnesium stearate (lubricant), coating (carbohydrate gum [cellulose], glycerin). | |
| Zinc Citrate | |
| Each Tablet Contains: | |
| Zinc (Citrate) | 50 mg |
| Non-medicinal Ingredients: Microcrystalline cellulose, stearic acid, vegetable grade magnesium stearate (lubricant), silica. | |
| PQQ-10® | |
| Each Softgel Contains: | |
| Coenzyme Q10 (Microorganism) (whole cell) | 200 mg |
| BioPQQ® Pyrroloquinoline Quinone (Disodium Salt) | 17.65 mg |
| SUN-E 900 Vitamin E (d-Alpha Tocopherol) (Helianthus annuus) (seed) | 5 IU (3.35 mg AT*) |
| *Alpha Tocopherol | |
| Non-medicinal Ingredients: Softgel (gelatin, glycerin, purified water, carob powder), organic flaxseed oil, yellow beeswax, non-GMO sunflower oil, lecithin. | |
| OptiMega-3® with Vitamin D3 | |
| Each Enteripure® Softgel Contains: | |
| Fish Oil Concentrate (Anchovy, Sardine, and/or Mackerel) | 1425 mg |
| Omega-3 Fatty Acids | 900 mg |
| Eicosapentaenoic Acid (EPA) | 600 mg |
| Docosahexaenoic Acid (DHA) | 300 mg |
| Vitamin D3 (Cholecalciferol) | 1000 IU (25 mcg) |
| Non-medicinal Ingredients: Softgel (gelatin, glycerin, purified water, pectin), natural tocopherols. | |
| N-Acetyl-L-Cysteine | |
| Each Capsule Contains: | |
| NAC (N-Acetyl-L-Cysteine) (Free Form) | 600 mg |
| Non-medicinal Ingredients: Vegetarian capsule (carbohydrate gum [cellulose], purified water), microcrystalline cellulose, croscarmellose sodium, vegetable grade magnesium stearate (lubricant). | |
| B Complex-Pro | |
| Each Capsule Contains: | |
| Vitamin B1 (Thiamine Hydrochloride, Benfotiamine) | 31.69 mg |
| Vitamin B2 (Riboflavin 5’-Phosphate Sodium) | 10 mg |
| Niacin (Inositol Hexanicotinate) | 100 mg |
| Pantothenic Acid (Calcium d-Pantothenate) | 100 mg |
| Vitamin B6 (Pyridoxal 5’-Phosphate Monohydrate) | 25 mg |
| Vitamin B12 (Methylcobalamin) | 500 mcg |
| Folate (from (6S)-5-Methyltetrahydrofolic Acid (MTHF), Glucosamine Salt, Quatrefolic®) | 400 mcg |
| Biotin | 250 mcg |
| Choline Dihydrogen Citrate | 50 mg |
| Inositol (Inositol Hexanicotinate) | 50 mg |
| Non-medicinal Ingredients: Vegetarian capsule (carbohydrate gum [cellulose], purified water), microcrystalline cellulose, vegetable grade magnesium stearate (lubricant), silica, organic kale, organic alfalfa, organic cilantro leaf, organic parsley, caperberry, sprouted garlic, organic artichoke, organic black radish, organic dandelion, barley grass, pepper, organic celery seed, organic beetroot, organic tomato, wasabi rhizome, fresh freeze-dried sprouted broccoli, organic upland cress, daikon, red radish, organic cauliflower, organic cabbage, organic arugula, organic watercress leaf, grape, pomegranate, strawberry, organic cranberry, organic blueberry, raspberry, bilberry, organic Indian gooseberry, schizandra berry, red orange, organic acai berry, Theracurmin® curcumin, organic decaffeinated green tea extract, organic ginger rhizome, organic echinacea, organic oregano, organic peppermint, organic spearmint, organic spirulina, organic chlorella, red algae, blue green algae, kelp. |
Allergens:
Contains no artificial colours, preservatives, or sweeteners; no dairy, starch, sugar, wheat, gluten, yeast, soy, corn, egg, fish, shellfish, animal products, tree nuts, or GMOs. Suitable for vegetarians/vegans.
Recommended Use:
Recommended Adult Dose: 1 packet per day or as directed by a health care practitioner. Take with food, a few hours before or after taking other medications or natural health products. Consult a health care practitioner for use beyond 3 months.
Contraindications
L-Arginine Consult a health care practitioner prior to use if you are pregnant or breastfeeding, suffer from a cardiovascular disease and are attempting an increase in physical activity, or if you are taking medication for cardiovascular disease, erectile dysfunction, and/or blood thinners, if you have a renal/kidney disease, or if you are following a low protein diet. Consult a health care practitioner if your cardiovascular condition worsens. Do not use if you have had a heart attack/myocardial infarction. Some people may experience gastrointestinal discomfort (such as diarrhea). Keep out of reach of children.
Vitamin E 400 IU with Selenium Consult a health care practitioner prior to use if you have a liver disorder, a history of non-melanoma skin cancer, have cardiovascular disease, diabetes or cancer, or are taking blood thinners. Keep out of reach of children.
Mito AMPTM Do not use if you are pregnant or breastfeeding. Consult a health care practitioner prior to use if you are taking medications for diabetes, high blood pressure, seizures, or if you have diabetes, a seizure disorder, liver or kidney disease, or have been instructed to follow a low protein diet. Do not use if you are taking health products with a blood coagulation affect (e.g., blood thinners, clotting factor replacements, acetylsalicylic acid, ibuprofen, fish oils, vitamin E) as this may increase the risk of spontaneous bleeding. Keep out of reach of children.
Zinc For adult use only. Zinc supplementation can cause a copper deficiency. Keep out of reach of children.
CerebroVital PQQ-10® Consult a health care practitioner prior to use if you are pregnant or breastfeeding, or are taking blood pressure medication or blood thinners. Keep out of reach of children.
NAC &ALA Consult a health care practitioner prior to use if you are pregnant or breastfeeding, or if you have diabetes or kidney stones. Do not use this product if you are taking antibiotics or nitroglycerin. Keep out of reach of children.
B Complex-ProTM People sensitive to nicotinic acid may experience flushing of the skin that is generally mild and transient. Keep out of reach of children.
1. Amaral, A., Lourenço, B., Marques, M., et al. (2013). Mitochondria functionality and sperm
quality. Reproduction, 146(5), R163-74.
2. Cassina, A., Silveira, P., Cantu, L., et al. (2015). Defective Human Sperm Cells Are Associated with Mitochondrial Dysfunction and Oxidant Production. Biol Reprod, 93(5), 119.
3. Cheng, J.B., Zhu, J., Ni, F., et al. (2018). [L-carnitine Combined With Coenzyme Q10
for Idiopathic Oligoasthenozoospermia: A Double-Blind Randomized Controlled Trial].
Zhonghua Nan Ke Xue, 24(1), 33-38.
4. Safarinejad, M.R., Safarinejad, S., Shafiei, N., et al. (2012). Effects of the reduced form
of coenzyme Q10 (ubiquinol) on semen parameters in men with idiopathic infertility:
a double-blind, placebo controlled, randomized study. J Urol, 188(2), 526-31.
5. Balercia, G., Buldreghini, .E, Vignini, A., et al. (2009). Coenzyme Q10 treatment in infertile
men with idiopathic asthenozoospermia: a placebo-controlled, double-blind randomized
trial. Fertil Steril, 91(5), 1785-92.
6. El Sheikh, M.G., Hosny, M.B., Elshenoufy, A., et al. (2015). Combination of vitamin E
and clomiphene citrate in treating patients with idiopathic oligoasthenozoospermia:
A prospective, randomized trial. Andrology, 3(5), 864-7.
7. Safarinejad, M.R., Safarinejad, S. (2009). Efficacy of selenium and/or N-acetyl-cysteine
for improving semen parameters in infertile men: a double-blind, placebo controlled,
randomized study. J Urol, 181(2), 741-51.
8. Ciftci, H., Verit, A., Savas, M., et al. (2009). Effects of N-acetylcysteine on semen parameters
and oxidative/antioxidant status. Urology, 74, 73-6.
9. Jannatifar, R., Parivar, K., Roodbari, N.H., et al. (2019). Effects of N-acetyl-cysteine supplementation on sperm quality, chromatin integrity and level of oxidative stress in infertile men.
Reprod Biol Endocrinol, 17(1), 24.
10. Fatima, P., Begum, N., lshrat, S., et al. (2016). Zinc supplementation in male infertility.
Bangabandhu Sheikh Mujib Medical University Journal, 8(1), 9-13.
11. Omu, A.E., Al-Azemi, M.K., Kehinde, E.O., et al. (2008). Indications of the mechanisms
involved in improved sperm parameters by zinc therapy. Med Princ Pract, 17(2), 108-16.
12. Safarinejad, M.R. (2011). Effect of omega-3 polyunsaturated fatty acid supplementation
on semen profile and enzymatic anti-oxidant capacity of seminal plasma in infertile men
with idiopathic oligoasthenoteratospermia: a double-blind, placebo-controlled, randomised
study. Andrologia, 43(1), 38-47.
13. Kromhout, D., de Goede, J. (2014). Update on cardiometabolic health effects of ?-3 fatty
acids. Curr Opin Lipidol, 25(1), 85-90.
14. Toyama, K., Nishioka, T., Isshiki, A., et al. (2014). Eicosapentaenoic Acid combined with
optimal statin therapy improves endothelial dysfunction in patients with coronary artery
disease. Cardiovasc Drugs Ther, 28(1), 53-9.1. Amaral, A., Lourenço, B., Marques, M., et al. (2013). Mitochondria functionality and sperm
quality. Reproduction, 146(5), R163-74.
2. Cassina, A., Silveira, P., Cantu, L., et al. (2015). Defective Human Sperm Cells Are Associated with Mitochondrial Dysfunction and Oxidant Production. Biol Reprod, 93(5), 119.
3. Cheng, J.B., Zhu, J., Ni, F., et al. (2018). [L-carnitine Combined With Coenzyme Q10
for Idiopathic Oligoasthenozoospermia: A Double-Blind Randomized Controlled Trial].
Zhonghua Nan Ke Xue, 24(1), 33-38.
4. Safarinejad, M.R., Safarinejad, S., Shafiei, N., et al. (2012). Effects of the reduced form
of coenzyme Q10 (ubiquinol) on semen parameters in men with idiopathic infertility:
a double-blind, placebo controlled, randomized study. J Urol, 188(2), 526-31.
5. Balercia, G., Buldreghini, .E, Vignini, A., et al. (2009). Coenzyme Q10 treatment in infertile
men with idiopathic asthenozoospermia: a placebo-controlled, double-blind randomized
trial. Fertil Steril, 91(5), 1785-92.
6. El Sheikh, M.G., Hosny, M.B., Elshenoufy, A., et al. (2015). Combination of vitamin E
and clomiphene citrate in treating patients with idiopathic oligoasthenozoospermia:
A prospective, randomized trial. Andrology, 3(5), 864-7.
7. Safarinejad, M.R., Safarinejad, S. (2009). Efficacy of selenium and/or N-acetyl-cysteine
for improving semen parameters in infertile men: a double-blind, placebo controlled,
randomized study. J Urol, 181(2), 741-51.
8. Ciftci, H., Verit, A., Savas, M., et al. (2009). Effects of N-acetylcysteine on semen parameters
and oxidative/antioxidant status. Urology, 74, 73-6.
9. Jannatifar, R., Parivar, K., Roodbari, N.H., et al. (2019). Effects of N-acetyl-cysteine supplementation on sperm quality, chromatin integrity and level of oxidative stress in infertile men.
Reprod Biol Endocrinol, 17(1), 24.
10. Fatima, P., Begum, N., lshrat, S., et al. (2016). Zinc supplementation in male infertility.
Bangabandhu Sheikh Mujib Medical University Journal, 8(1), 9-13.
11. Omu, A.E., Al-Azemi, M.K., Kehinde, E.O., et al. (2008). Indications of the mechanisms
involved in improved sperm parameters by zinc therapy. Med Princ Pract, 17(2), 108-16.
12. Safarinejad, M.R. (2011). Effect of omega-3 polyunsaturated fatty acid supplementation
on semen profile and enzymatic anti-oxidant capacity of seminal plasma in infertile men
with idiopathic oligoasthenoteratospermia: a double-blind, placebo-controlled, randomised
study. Andrologia, 43(1), 38-47.
13. Kromhout, D., de Goede, J. (2014). Update on cardiometabolic health effects of ?-3 fatty
acids. Curr Opin Lipidol, 25(1), 85-90.
14. Toyama, K., Nishioka, T., Isshiki, A., et al. (2014). Eicosapentaenoic Acid combined with
optimal statin therapy improves endothelial dysfunction in patients with coronary artery
disease. Cardiovasc Drugs Ther, 28(1), 53-9.
